COPPER,COBALT AND NICKEL COMPLEXES AS ANTICANCER DRUGS
Ayurveda Rasashastra: Copper, Cobalt, and Nickel Complexes in Anticancer Applications
Ayurveda Rasashastra, the traditional Indian science of medicinal minerals, has been exploring the therapeutic potentials of various metallic compounds. Among them, copper, cobalt, and nickel complexes have shown promising anticancer properties.
Copper Complexes: Copper plays a crucial role in biological systems, and its complexes have demonstrated anticancer activities by inducing apoptosis in cancer cells. These complexes can inhibit tumor growth and metastasis due to their ability to enhance oxidative stress in cancer cells while sparing healthy tissues.
Cobalt Complexes: Cobalt is essential for the production of red blood cells and has found applications in cancer therapy. Cobalt complexes are known to interfere with DNA replication in rapidly dividing cancer cells, thus inhibiting their proliferation. Additionally, they can enhance the immune response against tumors.
Nickel Complexes: Nickel complexes possess unique properties that make them suitable candidates for anticancer drugs. They can bind to DNA and disrupt cellular processes, leading to cell cycle arrest in malignant cells. Furthermore, nickel has also been explored for its potential in targeting specific cancer pathways.
Research in Ayurveda Rasashastra continues to uncover the intricate mechanisms through which these metallic complexes operate. The combination of traditional knowledge and modern scientific approaches paves the way for developing innovative anticancer therapies inspired by ancient wisdom.